Bruker has introduced the next-generation solariX 2XR fourier transform mass spectrometer (FTMS) to accelerate extreme resolution mass spectrometry with mass resolving powers in the range of 1-10 million. The new solariX 2XR system further advances the revolutionary method of isotope fine structure (IFS) mass spectrometry by reducing the time necessary to acquire IFS mass spectra, and by making IFS analysis easy and routine for broad applicability in chemistry research.
Its novel OMEGA detection electronics effectively doubles the detected ion cyclotron frequencies, thereby cutting in half the required measurement time to obtain IFS in time-sensitive small molecule workflows such as LC/MS and MALDI MS imaging. This patented enhancement to the acclaimed ParaCell FTMS detector cell increases the resolving power even further to a record-breaking 1.2 million in one second at m/z 200, with excellent quantitative isotope ratio fidelity. The unique solariX 2XR system can also routinely acquire mass spectra with more than 10 million resolving power, providing clear separation of molecular details that cannot be resolved with any other technologies, for the analysis of extremely complex mixtures in petroleomics, dissolved organic matter (DOM), MS imaging, metabolomics or top-down proteomics.
The previous generation solariX XR FTMS introduced analytical chemists to powerful isotopic fine structure (IFS) analysis with unprecedented molecular sum formula specificity, where the exact elemental composition of a small molecule can be unambiguously obtained directly from extreme resolution mass spectra. In the last few years, this level of IFS specificity has quickly become a routine tool in small molecule analysis, whether in metabolomics, pharmaceutical research, forensics or small molecule MS imaging.