Waters Corporation has unveiled the software Proteolabels that is designed as an extension for Progenesis QI for proteomics users and researchers. It supports studies involving stable isotope labels, SILAC, and dimethyl labeling in duplex or triplex.
Proteolabels was engineered with a focus on performance and usability, empowering scientists to explore their data and achieve high-quality results. The workflow is built upon the Progenesis QI for proteomics co-detection feature, in which several features aligned across LC-MS run to improve sensitivity and reproducibility. It makes a first pass through the data to suggest optimal parameters, simplifying the analysis.
Proteolabels contains novel metrics for scoring the quality of pairs and triples detected, enabling users to measure the reliability of quantitation down to the level of each peptide. It can perform intelligent weighted averaging of different peptide-level signals to give more accurate protein-level quantitation results. It also contains a large number of QC metrics and data-plotting options, enabling users to interact and explore their data, and, where needed, make decisions as to how to arrive at the best protein set.
Waters is offering Proteolabels through an exclusive agreement with Omic Analytics.